PROGRAM
31st Midwest Enzyme Chemistry Conference
15 October 2011, University of Chicago
7:45 am: Registration and continental breakfast
Lobby of the Biological Sciences Learning Center (924 East 57th Street).
8:20 am: Welcome and introductory remarks: George Garcia, Program Chair
Lecture Room 109, Biological Sciences Learning Center
8:30 am: Lecture Session 1: Steven Firestine, Session Chair
Lecture Room 109, Biological Sciences Learning Center
8:30 Ryan Martinie Calvin College, Grand Rapids, MI
"Discovery of a Tyrosine-Cysteine Crosslink Containing Protein Guided by Chemical Bioinformatics"
9:00 Shu Xu University of Toledo, OH
"Crystal Structure of 12-Lipoxygenase Catalytic Domain-Inhibitor Complex Identifies a Substrate Binding Channel for Catalysis"
9:30 Mishtu Dey University of Iowa, Iowa City, IA
"Structural and Biochemical Investigation of Metalloenzyme Mechanisms"
10:00 am: Coffee Break
10:20 am: Lecture Session 2: Garry Dotson, Session Chair
Lecture Room 109, Biological Sciences Learning Center
10:20 Daniel Rosten University of Iowa, Iowa City, IA
"Using Kinetic Isotope Effects to Assess Dynamic Motions of the Substrates in Enzymatic H-Transfers"
10:50 Oleg Tsodikov University of Michigan, Ann Arbor, MI
"Structure and mechanism of an unusual redox-controlled protease Rv3671c from Mycobacterium tuberculosis"
11:20 Henry Miziorko University of Missouri-Kansas City, MO
"Mechanistic, structural, and functional correlations for mevalonate diphosphate decarboxylase, a key enzyme in isoprenoid biosynthesis: Implications for related reactions catalyzed by GHMP kinase family enzymes"
11:50 am: Lunch:
Box lunch or as you please
1:30 pm: Lecture Session 3: Graham Moran, Session Chair
Lecture Room 109, Biological Sciences Learning Center
1:30 Minae Mure University of Kansas, Lawrence, KS
"Human Lysyl Oxidase-like 2 in Breast Cancer Metastasis"
2:00 Lawrence Gray University of Iowa, Iowa City, IA
"The transport kinetics and selectivity of HpUreI, the urea channel from Helicobacter pylori"
2:30 Miguel Ballicora Loyola University, Chicago, IL
"Evolution of Subunit Roles in the ADP-Glucose Pyrophosphorylase from Ostreococcus tauri: Restoring a “Deficient” Allosteric Site"
3:00 Bekir Eser University of Michigan, Ann Arbor, MI
"An Unusual Nonheme Diiron Reaction: Oxygen Independent Production of Hydrocarbons by a Cyanobacterial Aldehyde Decarbonylase"
3:30 pm: Closing remarks Marvin Makinen, Local Arrangements Chair
3:40 pm: Poster session
W301, Gordon Center for Integrative Science (929 East 57th Street)
6:00 pm: End